Unshared and Shared Frailty Models
نویسندگان
چکیده
منابع مشابه
Shared frailty models for recurrent events and a terminal event.
There has been an increasing interest in the analysis of recurrent event data (Cook and Lawless, 2002, Statistical Methods in Medical Research 11, 141-166). In many situations, a terminating event such as death can happen during the follow-up period to preclude further occurrence of the recurrent events. Furthermore, the death time may be dependent on the recurrent event history. In this articl...
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Pompe disease, an inherited deficiency of lysosomal acid α-glucosidase (GAA), is a severe metabolic myopathy with a wide range of clinical manifestations. It is the first recognized lysosomal storage disorder and the first neuromuscular disorder for which a therapy (enzyme replacement) has been approved. As GAA is the only enzyme that hydrolyses glycogen to glucose in the acidic environment of ...
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When analyzing correlated time to event data, shared frailty (random effect) models are particularly attractive. However, the estimation of such models has proved challenging. In semiparametric models, this is further complicated by the presence of the nonparametric baseline hazard. Although recent years have seen an increased availability of software for fitting frailty models, most software p...
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There are certain assumptions about the baseline distribution and distribution of frailty. Mostly Weibull distribution is considered for baseline hazard but we consider some different baseline distributions. Mostly assumption of gamma distribution is considered for frailty distribution. In this paper also, we consider gamma distribution as frailty distribution and two different baseline distrib...
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ژورنال
عنوان ژورنال: Alphanumeric Journal
سال: 2016
ISSN: 2148-2225
DOI: 10.17093/aj.2016.4.1.5000163276